CDE Catalog

View and download available CureSCi CDEs using filters below. For best results, clear form between searches.

Displaying 5051 - 5075 of 5231
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The search results below can be downloaded by clicking the checkboxes on the far right side of the table. Select the header checkbox to select all CDEs listed on the first page. Then choose CDE Detailed Report from the Choose an operation dropdown menu.
CDE ID CDE Name Definition Classification Version Number Version Date CRF Name ©, ® or TM Disease Name Sub Disease Name
C60533 Gene editing on target indel bone marrow CD34 plus cell count

Count of on-target indels in gene editing of bone marrow CD34+ cells.

Supplemental 1.00 2021-04-23 11:40:19.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60649 Gene editing off target indel bone marrow colony forming cell count

Count of off-target indels in gene editing of bone marrow colony forming cells (CFC).

Core 1.00 2021-04-23 11:40:19.0 Gene Product Follow-Up Sickle Cell Disease Sickle Cell Disease
C60534 Gene editing on target indel bone marrow colony forming cell count

Count of on-target indels in gene editing of bone marrow colony forming cells (CFC).

Supplemental 1.00 2021-04-23 11:40:19.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60535 Gene editing off target interrogation bioinformatic type

Type of bioinformatic method employed in interrogating off-target gene-editing results.

Supplemental 1.00 2021-04-23 11:50:01.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60536 Gene editing off target interrogation bioinformatic type other text

The free-text field related to "Gene editing off target interrogation bioinformatic type", specifying other text.

Supplemental 1.00 2021-04-23 11:50:01.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60537 Gene editing off target site screen count

Count of off-target gene editing sites screened.

Supplemental 1.00 2021-04-23 11:57:22.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60538 Gene editing off target site confirm count

Count of off-target gene editing sites confirmed.

Supplemental 1.00 2021-04-23 11:57:22.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60539 Gene editing off target site confirm GUIDE seq check indicator

Indicator of whether confirmation of off-target gene editing sites involved checking by GUIDE-seq.

Supplemental 1.00 2021-04-23 11:59:58.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60540 Gene editing off target site confirm next generation sequencing indicator

Indicator of whether confirmation of off-target gene editing sites was obtained by next-generation sequencing (NGS).

Supplemental 1.00 2021-04-23 11:59:58.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60541 Gene editing off target site confirm other method indicator

Indicator of whether confirmation of off-target gene editing sites was obtained by another method.

Supplemental 1.00 2021-04-23 11:59:58.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60542 Gene editing off target site confirm other method indicator other text

The free-text field related to "Gene editing off target site confirm other method indicator" specifying other text.

Supplemental 1.00 2021-04-23 11:59:58.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60543 Gene editing off target site acceptable rate confirm indicator

Indicator of whether an acceptable editing rate was confirmed for each off-target gene editing site.

Supplemental 1.00 2021-04-23 12:08:45.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60544 Gene editing off target site dominant location

Location(s) of the dominant off-target gene editing site(s).

Supplemental 1.00 2021-04-23 13:04:33.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60545 Gene editing off target site dominant location type

Type of location of dominant off-target gene editing site

Supplemental 1.00 2021-04-23 13:06:18.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60546 Gene editing site translocation on off target cytogenetic detection indicator

Indicator of whether gene editing translocations between on-target and off-target sites were detected by cytogenetics.

Supplemental 1.00 2021-04-23 13:10:07.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60547 Gene editing site translocation on off target cytogenetic detection other text

The free-text field related to "Gene editing site translocation on off target cytogenetic detection indicator" specifying other text.

Supplemental 1.00 2021-04-23 13:15:40.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60548 Gene editing site translocation on off target droplet digital polymerase chain reaction detection indicator

Indicator of whether gene editing translocations between on-target and off-target sites were detected by droplet digital polymerase chain reaction (PCR).

Supplemental 1.00 2021-04-23 13:18:53.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60549 Gene editing site translocation on off target droplet digital polymerase chain reaction detection limit text

Text field for capturing the droplet digital polymerase chain reaction (PCR) detection limit for translocations of on target and off target gene editing sites.

Supplemental 1.00 2021-04-23 13:24:46.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60550 Gene editing site translocation on off target droplet digital polymerase chain reaction detection frequency text

Text field for reporting the frequency of detection of translocation of on target and off target gene editing sites using droplet digital polymerase chain reaction (PCR).

Supplemental 1.00 2021-04-23 13:29:02.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60551 Gene editing site translocation clonality monitor method type

Type of method used to monitor clonality in translocation of gene editing sites.

Supplemental 1.00 2021-04-23 13:32:03.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60552 Gene editing site translocation clonality monitor method type other text

The free-text field related to "Gene editing site translocation clonality monitor method type", specifying other text.

Supplemental 1.00 2021-04-23 13:35:25.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60553 Gene editing any associated cell clone minimum 20 percent clone population indicator

Indicator of whether any cell clone(s) associated with gene editing comprise >=20 percent of the population of clones.

Supplemental 1.00 2021-04-23 13:38:09.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60554 Gene editing off target cell clone minimum 20 percent clone population gene location

Location of the gene containing, or nearest flanking gene to, the site of the off-target gene-editing clone that comprises >=20 percent of the population of all clones.

Supplemental 1.00 2021-04-23 13:41:43.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60555 Gene editing off target cell clone minimum 20 percent clone population proportion value

Value, as a percentage, of the proportion of the population of clones that is comprised by off-target gene-editing clones with a proportion >= 20 percent.

Supplemental 1.00 2021-04-23 13:45:16.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
C60556 Gene editing off-site target clone minimum 20 percent representation genetic location

Location, relative to other genes on a DNA strand, of any clone(s) having >=20 percent representation within the population of clones.

Supplemental 1.00 2021-04-23 13:53:51.0 Genotoxicity Sickle Cell Disease Sickle Cell Disease
Displaying 5051 - 5075 of 5231